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Jason H. Pomerantz, M.D.

Jason H. Pomerantz, M.D.

Associate Professor of Surgery
Division of Plastic and Reconstructive Surgery
Co-chair, Department of Surgery Research Committee
Surgical Director, Craniofacial Center
Director, Pomerantz Lab

Contact Information

UCSF Medical Center
Division of Plastic & Reconstructive Surgery
(415) 353-4389 phone
(415) 353-4330 fax
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  • 1990-1994 University of Pennsylvania, B.A. Biology
  • 1994-2000 Albert Einstein College of Medicine, M.D.
  • 2000-2001 University of California-San Francisco, Intern General Surgery
  • 2001-2003 University of California-San Francisco, Residency General Surgery
  • 2006-2008 University of California-San Francisco, Residency Plastic Surgery
  • 1996-1998 Howard Hughes Medical Institute, Researh Training Fellowship
  • 2008-2009 University of Washington, Seattle, Craniofacial Surgery Fellowship
  • 2003-2006 Stanford University, Postdoctoral Fellowship
  • American Board of Plastic Surgery 2010
  • Cleft lip and Palate
  • Congential Deformities
  • Craniofacial Surgery
  • Craniosynostosis
  • Pediatric Plastic Surgery
  • Traumatic facial injuries
  • Cancer
  • Cellular Growth Control
  • Muscle Regeneration
  • Nuclear Reprogramming
  • Stem Cell Biology

Jason Pomerantz, M.D. is an associate professor in the Division of Plastic and Reconstructive Surgery surgical director of the UCSF Craniofacial Center, and Director of the Pomerantz Lab. Dr. Pomerantz treats congenital and acquired deformities of the head and face, in both adults and children, including cleft lip and palate, craniosynostosis, and traumatic facial injuries. Dr. Pomerantz's NIH-funded research program focuses on the investigation of basic and translational aspects of tissue regeneration relevant to regeneration medicine. 

Dr. Pomerantz earned his medical degree at the Albert Einstein College of Medicine. He completed a residency at UCSF, a postdoctoral research fellowship in regeneration biology at Stanford University, and a fellowship in craniofacial surgery at the University of Washington.

With foundations in muscle, stem cell and cancer biology, his laboratory aims to develop novel approaches that will impact the treatment of structural disorders and deformities. Dr. Pomerantz is a researcher at the UCSF Program in Craniofacial  Biology (PCB), and has affiliations with the UCSF Biomedical Sciences (BMS) Graduate Program, and The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF.

Ultimately, Dr. Pomerantz hopes to identify the genes responsible for regeneration, genes that have evolved differently between species. This has implications for the reconstruction of damaged or missing tissue resulting from congenital abnormalities and those acquired as a result of trauma.

The research program of our lab is closely intertwined with regenerative medicine. With foundations in muscle and cancer biology, we are investigating regenerative mechanisms including stem cell development and de-differentiation. By employing model organisms such as zebrafish and mouse and extending discoveries to human cells and tissues, we hope to gain fundamental insight that can be translated into clinical advances, most notably solving the structural and reconstructive problems of the limbs, face, and head, whether congenital or acquired.

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  • Regeneration and Differentiation Potential of Heterogeneous Human Satellite Cells
    Sponsor:
    Sponsor ID:
    Funding Period:
    Sep 2017
    -
    Aug 2022
    Principal Investigator
  • Mechanisms Underlying Plasticity of Gene Expression
    Sponsor:
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    Funding Period:
    Sep 2004
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    Aug 2006
    Principal Investigator
MOST RECENT PUBLICATIONS FROM A TOTAL OF 47
Data provided by UCSF Profiles, powered by CTSI
  1. Lee S, Hesse R, Tamaki S, Garland C, Pomerantz JH. Human ARF Specifically Inhibits Epimorphic Regeneration in the Zebrafish Heart. Genes (Basel). 2020 Jun 18; 11(6). View in PubMed
  2. Barruet E, Garcia SM, Striedinger K, Wu J, Lee S, Byrnes L, Wong A, Xuefeng S, Tamaki S, Brack AS, Pomerantz JH. Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. Elife. 2020 Apr 01; 9. View in PubMed
  3. Trentesaux C, Striedinger K, Pomerantz JH, Klein OD. From gut to glutes: The critical role of niche signals in the maintenance and renewal of adult stem cells. Curr Opin Cell Biol. 2020 Apr; 63:88-101. View in PubMed
  4. Balkin DM, Poranki M, Forester CM, Dorsey MJ, Slavotinek A, Pomerantz JH. TASP1 mutation in a female with craniofacial anomalies, anterior segment dysgenesis, congenital immunodeficiency and macrocytic anemia. Mol Genet Genomic Med. 2019 09; 7(9):e818. View in PubMed
  5. Nguyen AB, Grimes B, Neuhaus J, Pomerantz JH. A Cross-sectional Study of the Association between Homelessness and Facial Fractures. Plast Reconstr Surg Glob Open. 2019 Jun; 7(6):e2254. View in PubMed
  6. View All Publications
Data provided by UCSF Profiles, powered by CTSI

 

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